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Batch-specific CoA available on request.
High-purity calcium folinate for oncology, detoxification, and nutritional applications
Calcium folinate (also known as leucovorin calcium) is the calcium salt of folinic acid, serving as a crucial antidote in methotrexate therapy and a biomedically active form of folate. Our pharmaceutical-grade product meets EP/USP standards for therapeutic use in cancer treatment and folate deficiency management.
1. PRODUCT IDENTIFICATION
| Parameter | Specification |
|---|---|
| Chemical Name | Calcium (2S)-2-[[4-[(2-amino-5-formyl-4-oxo-5,6,7,8-tetrahydro-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioate |
| CAS Number | 6035-45-6 |
| Molecular Formula | C₂₀H₂₁CaN₇O₇ |
| Molecular Weight | 511.50 g/mol |
| Therapeutic Category | Antidote/Chemotherapy Adjuvant |
2. QUALITY SPECIFICATIONS
| Test Parameter | USP | EP | JP |
|---|---|---|---|
| Assay (HPLC) | 97.0-102.0% | 98.0-102.0% | 98.0-102.0% |
| Related Substances | ≤2.0% | ≤1.5% | ≤1.5% |
| Endotoxins | <0.5 EU/mg | <0.5 EU/mg | <0.5 EU/mg |
| Sterility | Complies USP <71> | Complies EP 2.6.1 | Complies JP 4.06 |
3. PHYSICOCHEMICAL PROPERTIES
| Property | Specification |
|---|---|
| Appearance | White to pale yellow powder |
| Solubility | Freely soluble in water (>50 mg/mL) |
| pH (1% solution) | 6.5-7.5 |
| Optical Rotation | +14° to +20° |
4. HANDLING & STORAGE
5. SAFETY INFORMATION
6. PACKAGING OPTIONS
| Format | Quantity | Special Features |
|---|---|---|
| Lyophilized vials | 1g/vial | Sterile, ready-to-use |
| Amber glass bottles | 100g | Nitrogen flushed |
| Aluminum pouches | 1kg | Vacuum sealed |
✔ Oncology therapeutics ✔ Pharmaceutical formulations ✔ Clinical research ✔ Diagnostic reagents
For pricing and minimum order quantities (MOQ), please contact our sales team. Custom formulations and packaging available upon request.
This specification sheet provides comprehensive technical data while maintaining clear readability for pharmaceutical buyers and researchers. Would you like any modifications to emphasize particular aspects of the product?
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For detailed information on the Minimum Order Quantity (MOQ) for a specific product or to discuss custom packaging solutions, please contact our sales team.
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Reischbio provides confidential custom synthesis services, structured for innovative companies requiring unique and proprietary molecules. Our expert chemists leverage state-of-the-art reaction technologies to tackle complex, multi-step synthesis projects, from milligrams to multi-kilogram scale. Governed by strict IP protection protocols, we function as a seamless extension of your R&D team. Our agile project management and transparent communication ensure projects are delivered on-time and on-spec. With our bespoke chemistry solutions, we empower you to overcome scientific challenges, secure critical IP, and accelerate your path to innovation.
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